Mulberry leaf extract 1-DNJ 5%

 Mulberry leaf extract is produced from the processing of mulberry leaf powder obtained from the first to third new leaves on the branches of mulberry trees in late spring or before the first frost.
Mulberry Leaf Extract DNJ (1-Deoxynojirimycin) is a natural compound found in mulberry leaves. DNJ has gained interest in the scientific community due to its potential health benefits.
DNJ is known for its ability to inhibit the activity of the enzyme α-glucosidase, which is involved in the breakdown of complex carbohydrates into glucose in the digestive system. By inhibiting this enzyme, DNJ can help regulate blood sugar levels and prevent rapid spikes in glucose after meals.
Several studies have suggested that DNJ may have anti-diabetic properties and can be used as a natural supplement for managing diabetes. It is believed to improve insulin sensitivity, promote glucose uptake by cells, and reduce glucose absorption from the intestine.
In addition to its potential anti-diabetic effects, DNJ has also shown antioxidative and anti-inflammatory properties. It may help protect against oxidative stress and reduce inflammation in the body, which are associated with various chronic diseases.
Meanwhile the extract contains  others various physiologically active substances such as mulberry leaf flavonoids, mulberry leaf polyphenols, mulberry leaf polysaccharides and GABA, among others. It is used for the prevention and treatment of cardiovascular and cerebrovascular diseases, hyperlipidemia, diabetes, obesity, and anti-aging.
The active components of the mulberry leaf have effects such as regulating blood sugar, dispersing wind-heat, moistening the lungs, clearing the liver, and brightening the eyes. It is used for conditions such as wind-heat common cold, lung heat cough, headaches, dizziness, red and swollen eyes, and blurred vision. The active ingredients in mulberry leaf also have antioxidant, anti-aging, antibacterial, and moisturizing effects.

Raw Material & Extraction Foundation
The foundation of our Mulberry Extract begins with carefully selected mulberry leaves harvested from controlled plantations with consistent agronomic practices. These leaves are chosen for optimal phytochemical profiles—rich in flavonoids, alkaloids (in the case of 1-deoxynojirimycin), and other plant metabolites. After harvesting, the leaves are cleaned, dried and processed by our plant extract manufacturers through a refined extraction procedure that isolates the active compounds. The process may include water or low-impact solvent extraction, concentration, purification and spray-drying into a fine powder. The resulting mulberry powder is then standardized to deliver consistent functional properties. As a plant extract supplier, we maintain full traceability: from raw leaf sourcing, batch logging, extraction profiling, through to milling, packaging and quality release. This ensures that the botanical lineage—from mulberry leaf extract or mulberry powder format—is fully maintained and documented. This manufacturing backbone supports the integrity of the ingredient and allows the brand using it to claim botanical origin, clean-label status and premium functionality.

Functional Performance & Formulation Integration
Mulberry Extract brings a unique functional profile that aligns with consumer awareness around botanical wellness and metabolic-health support. For example: mulberry leaf extract has been associated with supporting healthy glucose metabolism, antioxidant status, vascular wellness and general plant-based wellness. The powder or extract format is highly suitable for formulators: it integrates into capsules, tablets, beverage powders, functional drink mixes, snack bars, gummies or fortified foods. Because our mulberry powder has mild flavour and good mixability, it can be used in both food and solid dosage formats with minimal sensory disruption. As a plant extract supplier, we provide the technical documentation and batching support needed for OEM/ODM applications—ensuring your formulation has a consistent base ingredient, whether you use the mulberry extract or mulberry powder variant. In addition, working with seasoned plant extract manufacturers means you benefit from production scale, specification control, and formulation guidance for your product development.

Quality Control & Supply Chain Assurance
Quality assurance is integral to our Mulberry Extract offering. Each batch is tested and verified by our plant extract manufacturers using advanced instrumentation (HPLC, TLC, UV-Vis, GC where applicable) to confirm identity, purity, and potency. Heavy metals, microbial safety, residual solvent analysis, moisture, particle size, flowability and stability testing are all part of our release process, demonstrating our commitment as a plant extract supplier delivering commercial-grade ingredients. Our facility, production lines and warehousing are built to support large-volume output with consistent quality, enabling OEM/ODM projects and global supply chains. We provide complete documentation including Certificate of Analysis (COA), Material Safety Data Sheet (MSDS), traceability records and specification sheets, empowering our clients to fulfil regulatory, labeling and quality-management requirements.

2. Specification

Standard Specifications

Appearance    ：         Fine brown powder

Active Component  ：  1%-20.0%   1-  DNJ by HPLC

Solubility ：                   Soluble in water

Solvent Used   ：           Ethanol and/or water

Solvent Residue  ：       EU/USP regulations

Pesticides Residue ：     EU/USP regulations

Heavy Metal     ：         EU/USP regulations

Microorganism :           EU/USP regulations

Features
Naturale Bioparma  Our products are semi-finished raw materials that need further processing, and we do not recommend direct personal use. Please follow your doctor's instructions or formula for the specific dosage or usage.It is made from mulberry branches and leaves of vegetable mulberries, which are deeply processed by special technology. They are non-polluting, non-additive, pure and natural, and also contain high content and high purity DNJ, which has an excellent sugar control effect.

◆ High Purity: The product is available in purity levels of 1% or 5% By HPLC ,“EU & US FDA compliant”
◆ Natural Source: The extract is derived from100% natural mulberry leaves, which are known for their rich content of DNJ.
◆ Friendly Taste & Water Soluble
◆ Innovation herbal diabetic treatment
◆Effectively Decrease the PBGpostpandul Blood Gcos)
◆Safely be used over thousands years
◆Improve diabetic complications
◆Animal & Cinical Study Supported
◆ Growing demand in functional beverages and nutricosmetics”

Aplication

4. Production Details

5. Product Qualification

“About Naturale Biopharma – 20 years’ expertise in plant extracts, GMP facility, serving 300+ clients worldwide,Our Mulberry Leaf Extract DNJ(1-Deoxynojirimycin) is produced in a clean working environment and every step of the process beginning with the farming pool to packaging is conducted by highly qualified professionals. Both processes of manufacture and the product itself meet all international standards.